Product Name: Oral Active Pharmaceutical Ingredients Spironolactones 52-01-7 Used as a Diuretic Model NO.: 52-01-7 Purity: >99% State: Solid Suitable for: Adult Certification: USP, BP Customized: Customized Powder: Yes CAS Number: 52-01-7 Key Words: Spironolactones Type: Pharmaceutical Intermediates Usage: Pharmaceutical Raw Material Mf: C24h32o4s Appearance: White Powder Alias: Spironolactones Manufacturer: Spironolactones Manufacturer Assay: 99% Spironolactones Package: 1-2 Kg / Aluminum Foil Bag, 25kg/ Drum, as Require Trademark: XRD Transport Package: 1-2 Kg / Aluminum Foil Bag, 25kg/ Drum, as Require Specification: 99% Spironolactones Origin: China HS Code: 3002200000 Product Description Oral Active Pharmaceutical Ingredients Spironolactones 52-01-7 Used as a DiureticQuick detailName: SpironolactonesCAS No.: 52-01-7Formula: C24H32O4SMolecular Weight: 416.62Density: 1.24 g/cm3Melting Point: 207-208 °C(lit.)Boiling Point: 597 °C at 760 mmHgFlash Point: 302.3 °CSolubility: practically insoluble in waterAppearance: White to Off White SolidUsed as a diuretic, lactone (spironolactones), the active metabolite. Inhibition of aldosterone biosynthesis. Wow effect of blockers for Pakistan It is a synthetic 17-lactone steroid which is a renal competitive aldosterone antagonist in a class of pharmaceuticals called potassium-sparing diuretics, used primarily to treat ascites in patients with liver disease, low-renin hypertension, hypokalemia.DescriptionAldactone removes excess fluid from the body in congestive heart failure, cirrhosis of the liver, and kidney disease.It also can be used in combination with other drugs to treat elevated blood pressure, and for treating diuretic-induced low potassium (hypokalemia).Aldactone also is used to counteract the effects of excessive adrenal aldosterone production (hyperaldosteronism). Aldosterone overproduction can occur from a tumor in the adrenal gland or enlarged adrenal glands (hyperplasia of the adrenal glands).Spironolactones Specification:Ref. standardEP8/USP39Analysis itemsSpecificationResultsAppearancewhite or yellowish-white powderWhite powderSolubilityPractically insoluble in water, soluble in ethanol(96 per cent).CompliesIdentificationA/B/C Meet the requirementsCompliesSpecific rotation- 41 to -46°(EP)/-41 to -45°(USP)-43°Loss on dryingNot more than 0.5%0.08%Sulfated ashNot more than 0.1%0.03%Impurity A andImpurity CNot more than 0.2%N.DImpurity F andImpurity ENot more than 0.3%N.DImpurity DNot more than 0.15%N.DImpurity INot more than 0.5%N.DOther arbitrary unknown impuritiesNot more than 0.1%CompliesTotal impuritiesNot more than 0.7%0.15%Ordinary impurities(USP)Not more than 2.0%0.05%Free thiol compounds(EP)Not more than 0.05 mlCompliesFree mercapto compounds(USP)Not more than 0.1mlCompliesChromium(EP)50ppmNot more than 50ppmCompliesAssay97.0%~103.0%(USP)/97.5-102%(EP)99.9% (USP) /100.1% (EP)Fineness95% Not more than 20 μmCompliesConclusionQualifiedPacking:Advantages:HongkongXinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is our philosophy. We have Flexible and Untraceable payment terms. As a leading manufacture, our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries.1. Quality.Every batch of steroid powders have tobetested by our QC(quality control) before they are allowed to sell.2. Delivery We have stock, so we can delivery quickly at the very day when receive the payment. Within 24 hours after receiving the payment Lead time 4 or 7 days.3. Discreet package Safelyand Professionally Disguised Package Guaranteed. For your safety and toinsure delivery all products will be packed in a discreet way to prevent any suspicions, no steroids related name will appear on the parcels. high successful delivery rate4. Warm after-sale service Any of your question would be solved for the first as soon as possible.Oral Active Pharmaceutical Ingredients Spironolactones 52-01-7 Used as a Diuretic